| Identification | Back Directory | [Name]
Azido-PEG3-PFP ester | [CAS]
1807530-07-9 | [Synonyms]
N3-PEG3-PFP
N3-PEG3-PFP ESTER
N3-PEG3-C2-PFP ester
Azido-PEG3-PFP ester
perfluorophenyl 3-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)propanoate | [Molecular Formula]
C15H16F5N3O5 | [MDL Number]
MFCD26793779 | [MOL File]
1807530-07-9.mol | [Molecular Weight]
413.3 |
| Hazard Information | Back Directory | [Description]
Azido-PEG3-PFP ester is a PEG reagent consistig of an azide and PFP ester moities. The azide is reactive with copper-catalyzed Click Chemistry reactions with propargyl, copper-free click chemistry with DBCO and BCN. The PFP ester is amine-reactive and is less susceptible toward hydrolysis compared to NHS ester. | [Uses]
N3-PEG3-C2-PFP ester is a nonclaevable 3-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs). N3-PEG3-C2-PFP ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | [IC 50]
Non-cleavable Linker |
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| Company Name: |
Nextpeptide Inc
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+86-0571-81612335 +8613336028439 |
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http://www.nextpeptide.com/ |
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