1807537-31-0

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1807537-31-0 Structure

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[MDL Number] MFCD28142466

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[Description] Benzyl-PEG6-CH2CO2tBu is a PEG linker containing a benzyl protecting group and a t-butyl group. Both the benzyl and t-butyl groups are acid labile. The hydrophilic PEG linker increases the water solubility of the compounds in aqueous solutions.
[Uses] BnO-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
[IC 50] PEGs
[References] [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

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