| Identification | Back Directory | [Name]
Benzyl-PEG6-Mes | [CAS]
1807539-07-6 | [Synonyms]
Benzyl-PEG5-Ms
Benzyl-PEG6-MS
Benzyl-PEG6-Mes
Benzyl-PEG5-Mes
CAS_1807539-07-6
Benzyl-PEG5-Mes AAA
3,6,9,12,15-Pentaoxahexadecan-1-ol, 16-phenyl-, 1-methanesulfonate | [Molecular Formula]
C18H30O8S | [MDL Number]
MFCD28976666 | [MOL File]
1807539-07-6.mol | [Molecular Weight]
406.49 |
| Hazard Information | Back Directory | [Description]
Benzyl-PEG6-Ms is a PEG linker containing a benzyl protecting group and a mesyl group. The benzyl moiety can be used as an alcohol protecting group and can be removed via hydrogenolysis. The mesyl group is a good leaving group for substitution reactions. The hydrophilic PEG linkers increase the water solubility of the compound in aqueous media. The water solubility properties of the PEG linker are enhanced with longer PEG chains. | [Uses]
Benzyl-PEG5-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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| Company Name: |
Henan Alfachem Co.,Ltd.
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0371-55051623 18137891487 |
| Website: |
www.chemicalbook.com/supplier/14555231/ |
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