ChemicalBook--->CAS DataBase List--->1807775-88-7

1807775-88-7

1807775-88-7 Structure

1807775-88-7 Structure
IdentificationBack Directory
[Name]

1H-Purine-2,6-dione, 3-[3-(dimethylamino)propyl]-3,7-dihydro-1-hydroxy-7-(2-phenylethyl)-
[CAS]

1807775-88-7
[Synonyms]

3-[3-(dimethylamino)propyl]-1-hydroxy-7-(2-phenylethyl)purine-2,6-dione
1H-Purine-2,6-dione, 3-[3-(dimethylamino)propyl]-3,7-dihydro-1-hydroxy-7-(2-phenylethyl)-
[Molecular Formula]

C18H23N5O3
[MOL File]

1807775-88-7.mol
[Molecular Weight]

357.41
Chemical PropertiesBack Directory
[Boiling point ]

604.6±65.0 °C(Predicted)
[density ]

1.30±0.1 g/cm3(Predicted)
[form ]

Solid
[pka]

7.51±0.20(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

Caf1-IN-1 (Compound 8j) is inhibitor for ribonuclease Caf1 with an IC50 of 0.59 μM. Caf1-IN-1 is also a weak inhibitor for poly(A)-specific ribonuclease (PARN) with IC50 of 23.9 μM[1].
[References]

[1] Jadhav GP, et al., Discovery, synthesis and biochemical profiling of purine-2,6-dione derivatives as inhibitors of the human poly(A)-selective ribonuclease Caf1. Bioorg Med Chem Lett. 2015 Oct 1;25(19):4219-24. DOI:10.1016/j.bmcl.2015.07.095
1807775-88-7 suppliers list
Company Name: Angel Pharmatech, Ltd.  
Tel: 17317130613
Website: http://www.angelpharmatech.com
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Website: https://www.targetmol.cn/
Tags:1807775-88-7 Related Product Information

  • HomePage | Member Companies | Advertising | Contact us | Previous WebSite | MSDS | CAS Index | CAS DataBase | Privacy | Terms | About Us
  • All products displayed on this website are only for non-medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.
    According to relevant laws and regulations and the regulations of this website, units or individuals who purchase hazardous materials should obtain valid qualifications and qualification conditions.
  • Copyright © 2023 ChemicalBook All rights reserved.