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1808119-16-5

1808119-16-5 Structure

1808119-16-5 Structure
IdentificationBack Directory
[Name]

Halo-DBCO
[CAS]

1808119-16-5
[Synonyms]

Halo-DBCO
Dibenz[b,f]azocine-5(6H)-butanamide, N-[2-[2-[(6-chlorohexyl)oxy]ethoxy]ethyl]-γ-oxo-
N-(2-(2-[(6-chlorohexyl)oxy]ethoxy)ethyl)-4-(11,12-didehydrodibenzo[b,f]azocin-5(6H)-yl)-4-oxobutanamide
[Molecular Formula]

C29H35ClN2O4
[MOL File]

1808119-16-5.mol
[Molecular Weight]

511.05
Chemical PropertiesBack Directory
[Boiling point ]

765.5±60.0 °C(Predicted)
[density ]

1.21±0.1 g/cm3(Predicted)
[form ]

Solid
[pka]

15.14±0.46(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

Halo-DBCO is a click chemistry reagent containing dibenzocyclooctyne (DBCO). Halo-DBCO can be used as a ligand to react with HaloTag to form covalent HaloTag ligand couples[1].
[References]

[1] Teng X, et al. ClickRNA-PROTAC for Tumor-Selective Protein Degradation and Targeted Cancer Therapy. J Am Chem Soc. 2024 Oct 9;146(40):27382-27391. DOI:10.1021/jacs.4c06402
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