| Identification | Back Directory | [Name]
PAPP | [CAS]
1814-64-8 | [Synonyms]
163
LY165
LY-165
LY 165
p-Nh2-pe-tfmpp
PAPP (LY-165,163) SELECTIVE 5-HT1A SERO
1-(2-(4-Aminophenyl)ethyl)-4-(3-trifluoromethylphenyl)piperazine
4-[2-[4-[3-(Trifluoromethyl)phenyl]-1-piperazinyl]ethyl]benzenamine
Benzenamine, 4-(2-(4-(3-(trifluoromethyl)phenyl)-1-piperazinyl)ethyl)-
PAPP, p-Aminophenethyl-m-trifluoromethylphenyl piperazine, 4-[2-[4-[3-(Trifluoromethyl)phenyl]-1-piperazinyl]ethyl]benzeneamine | [Molecular Formula]
C19H22F3N3 | [MDL Number]
MFCD00055098 | [MOL File]
1814-64-8.mol | [Molecular Weight]
349.39 |
| Chemical Properties | Back Directory | [Melting point ]
83-85 °C | [Boiling point ]
464.1±45.0 °C(Predicted) | [density ]
1.218±0.06 g/cm3(Predicted) | [solubility ]
0.1 M HCl: slightly soluble | [form ]
solid | [pka]
7.85±0.10(Predicted) | [color ]
off-white |
| Hazard Information | Back Directory | [Uses]
LY-165,163 is a selective 5-HT1A and 5-HT1D serotonin receptor antagonist. | [Definition]
ChEBI:LY-165163 is a N-arylpiperazine that is piperazine susbtituted by 2-(4-aminophenyl)ethyl and 3-(trifluoromethyl)phenyl groups at positions 1 and 4, respectively. It is a selective 5-HT1A serotonin receptor agonist and 5-HT1D serotonin receptor antagonist. It has a role as a geroprotector and a serotonergic agonist. It is a N-arylpiperazine, a N-alkylpiperazine, a member of (trifluoromethyl)benzenes, a substituted aniline and a primary arylamine. It is functionally related to a 1-(3-(trifluoromethyl)phenyl)piperazine. |
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| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
SIGMA-RBI
|
| Tel: |
800 736 3690 (Orders) |
| Website: |
www.sigma-aldrich.com |
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