| Identification | Back Directory | [Name]
Azidoacetic acid methyl ester | [CAS]
1816-92-8 | [Synonyms]
Methyl 2-azidoacetate 97%
Methyl 2-azidoacetate - M3461
Azidoacetic acid methyl ester
2-Azido-acetic acid Methyl ester
Acetic acid, 2-azido-, Methyl ester | [Molecular Formula]
C3H5N3O2 | [MDL Number]
MFCD01311034 | [MOL File]
1816-92-8.mol | [Molecular Weight]
115.091 |
| Chemical Properties | Back Directory | [Boiling point ]
35 °C | [density ]
1.182 g/mL at 25 °C | [refractive index ]
n20/D1.440 | [Fp ]
48℃ | [form ]
liquid | [InChI]
InChI=1S/C3H5N3O2/c1-8-3(7)2-5-6-4/h2H2,1H3 | [InChIKey]
RXYCUKSOYJWGPE-UHFFFAOYSA-N | [SMILES]
C(=O)(OC)CN=[N+]=[N-] |
| Hazard Information | Back Directory | [Uses]
- Methyl 2-azidoacetate is widely used as a precursor to build triazole derivatives via alkyne-azide click chemistry. Some of the examples include the synthesis of coumarin-triazole derivatives as potential antiplasmodial agents and macrocyclic triazole containing largazole analogs as histone deacetylases-1 (HDAC1) inhibitors.
- It can be used to synthesize various pyrrole derivatives by Knoevenagel condensation as in the synthesis of near-infrared boron dipyrromethene (BODIPY) donors for organic tandem solar cells.
- It can also be used in Hemetsberger-Knittel synthesis of substituted 5-, 6-, and 7-azaindoles.
- Synthesis of highly fluorescent pyreno[2,1-b]pyrroles using methyl 2-azidoacetate as one of the reagents.
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SAKEM LLP
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+91-9676889998 +91-9676889998 |
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www.sakem.co.in |
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Innovative Labs
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www.innovativelabsindia.com |
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