| Identification | Back Directory | [Name]
4H-Anthra[1,2-b]pyran-4,7,12-trione, 11-hydroxy-5-(hydroxymethyl)-2-[(1R)-1-methylpropyl]- | [CAS]
182232-96-8 | [Synonyms]
4H-Anthra[1,2-b]pyran-4,7,12-trione, 11-hydroxy-5-(hydroxymethyl)-2-[(1R)-1-methylpropyl]- | [Molecular Formula]
C22H18O6 | [MOL File]
182232-96-8.mol | [Molecular Weight]
378.37 |
| Hazard Information | Back Directory | [Uses]
Espicufolin is a neuroprotective substance that can be found in Streptomyces sp:cu39. Espicufolin can inhibit glutamate toxicity, thereby reducing or overcoming cerebral ischemic damage, with a toxicity EC50 value of 40 nM for N18-RE-105 cells. Espicufolin can be used in the study of neurodegenerative diseases[1]. | [References]
[1] J S Kim, et al. A novel neuronal cell protecting substance, espicufolin, produced by Streptomyces sp. cu39. J Antibiot (Tokyo). 1996 Sep;49(9):947-8. DOI:10.7164/antibiotics.49.947 |
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