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1824382-78-6

1824382-78-6 Structure

1824382-78-6 Structure
IdentificationBack Directory
[Name]

3-keto Sphinganine (d8:0) (hydrochloride
[CAS]

1824382-78-6
[Synonyms]

3-keto Sphinganine (d8:0) (hydrochloride
[Molecular Formula]

C8H18ClNO2
[MOL File]

1824382-78-6.mol
[Molecular Weight]

195.69
Chemical PropertiesBack Directory
[form ]

A solid
Hazard InformationBack Directory
[Description]

3-keto Sphinganine (d8:0) is a short-chain analog of the typical C18 chain-length 3-keto sphinganine (d18:0) . 3-keto Sphinganine (d18:0) is a lyso-sphingolipid formed by the condensation of L-serine and palmitoyl-CoA by serine palmitoyl transferase (SPT). Vitamin K deficiency inactivates SPT resulting in a decrease in the production of 3-keto sphinganine and other sphingolipids.1
[Uses]

3-Keto sphinganine (d8:0) hydrochloride is a biochemical reagent.
[References]

1. Batheja, A.D., Uhlinger, D.J., Carton, J.M., et al. Characterization of serine palmitoyltransferase in normal human tissues J. Histochem. Cytochem. 51(5),687-696(2003).
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