| Identification | Back Directory | [Name]
7-amino-2,3-dihydro-1H-inden-4-ol | [CAS]
1825352-65-5 | [Synonyms]
RG7916
Risdiplam
RO7034067
7-amino-2,3-dihydro-1H-inden-4-ol
4H-Pyrido[1,2-a]pyrimidin-4-one, 7-(4,7-diazaspiro[2.5]oct-7-yl)-2-(2,8-dimethylimidazo[1,2-b]pyridazin-6-yl)- | [Molecular Formula]
C22H23N7O | [MDL Number]
MFCD31657372 | [MOL File]
1825352-65-5.mol | [Molecular Weight]
401.46 |
| Chemical Properties | Back Directory | [density ]
1.50±0.1 g/cm3(Predicted) | [solubility ]
Soluble in DMSO | [form ]
solid | [pka]
9.41±0.20(Predicted) | [color ]
Light yellow to yellow | [InChI]
InChI=1S/C22H23N7O/c1-14-9-18(26-29-11-15(2)24-21(14)29)17-10-20(30)28-12-16(3-4-19(28)25-17)27-8-7-23-22(13-27)5-6-22/h3-4,9-12,23H,5-8,13H2,1-2H3 | [InChIKey]
ASKZRYGFUPSJPN-UHFFFAOYSA-N | [SMILES]
C12C=CC(N3CC4(CC4)NCC3)=CN1C(=O)C=C(C1=NN3C=C(C)N=C3C(C)=C1)N=2 |
| Hazard Information | Back Directory | [Description]
Risdiplam is a survival of motor neuron 2 (SMN2) splicing modifier. | [Chemical Properties]
light yellow powder to yellow powder | [Uses]
RG 7916 is used in preparation of Imidazopyridazinyl Pyridopyrimidinones for treating spinal muscular atrophy.Gene splicing modulator. | [Side effects]
Body aches or pain, chest pain or tightness, chills, cough, ear congestion, fever, headache, loss of voice, runny or stuffy nose, sneezing, sore throat, trouble breathing, unusual tiredness or weakness and so on. | [storage]
0-4℃ for short term (days to weeks) or -20℃ for long term (months) |
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