| Identification | Back Directory | [Name]
3-Furancarboxylic acid, 5-[[[(6-ethoxy-3,4-dihydro-2H-1-benzopyran-3-yl)carbonyl]methylamino]methyl]-2-methyl- | [CAS]
1826337-40-9 | [Synonyms]
S07-2005 (racemic)
3-Furancarboxylic acid, 5-[[[(6-ethoxy-3,4-dihydro-2H-1-benzopyran-3-yl)carbonyl]methylamino]methyl]-2-methyl- | [Molecular Formula]
C20H23NO6 | [MOL File]
1826337-40-9.mol | [Molecular Weight]
373.41 |
| Hazard Information | Back Directory | [Uses]
S07-2005 racemic is a potent and selective aldo-keto reductase 1C3 (AKR1C3) inhibitor with an IC50 value of 0.13 μM and 0.75 μM for AKR1C3 and AKR1C4, respectively. S07-2005 racemic has potential as a chemotherapeutic potentiator for cancer agent resistance[1]. | [References]
[1] Siyu He, et al. Discovery of Novel Aldo-Keto Reductase 1C3 Inhibitors as Chemotherapeutic Potentiators for Cancer Drug Resistance. ACS Med. Chem. Lett. Jun 2022. |
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