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182821-27-8

182821-27-8 Structure

182821-27-8 Structure
IdentificationBack Directory
[Name]

SLV 306
[CAS]

182821-27-8
[Synonyms]

SLV 306
Daglutril
Daglutril - SLV 306
2-((S)-3-(1-((R)-2-(ethoxycarbonyl)-4-phenylbutyl)cyclopentanecarboxamido)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-1-yl)acetic acid
1H-1-Benzazepine-1-acetic acid, 3-[[[1-[(2R)-2-(ethoxycarbonyl)-4-phenylbutyl]cyclopentyl]carbonyl]amino]-2,3,4,5-tetrahydro-2-oxo-, (3S)-
[Molecular Formula]

C31H38N2O6
[MDL Number]

MFCD00951548
[MOL File]

182821-27-8.mol
[Molecular Weight]

534.64
Chemical PropertiesBack Directory
[Boiling point ]

802.3±65.0 °C(Predicted)
[density ]

1.25±0.1 g/cm3(Predicted)
[pka]

3.73±0.10(Predicted)
Hazard InformationBack Directory
[Uses]

Daglutril is a compound with the potential to regulate cytokine-induced endothelin-1 production in astrocytes. In studies, it has an inhibitory effect on the production of endothelin-1 induced by some cytokines and can be used as a tool to screen compounds that inhibit endothelin-1 production in astrocytes.
[References]

[1] Modulation of Cytokine-Induced Astrocytic Endothelin-1 Production as a Possible New Approach to the Treatment of Multiple Sclerosis DOI:10.3389/fphar.2019.01491
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