| Chemical Properties | Back Directory | [density ]
1.49±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | [pka]
12.99±0.70(predicted) | [Sequence]
Cyclo({d-Phe}-{2-Nal}-Arg-{d-Arg}-Arg-{d-Arg}-Gln) |
| Hazard Information | Back Directory | [Uses]
CPP9 is a small, amphipathic, cyclic cell penetrating peptide (CPP). CPPs bind directly to the plasma membrane phospholipids and enter mammalian cells via endocytosis, followed by efficient release from the endosome. CPP9 can be used for intracellular delivery of therapeutic agents and chemical probes[1]. | [References]
[1] Qian Z, et al. Discovery and Mechanism of Highly Efficient Cyclic Cell-Penetrating Peptides. Biochemistry. 2016 May 10;55(18):2601-12. DOI:10.1021/acs.biochem.6b00226 |
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