| Identification | Back Directory | [Name]
17(S)-HETE | [CAS]
183509-25-3 | [Synonyms]
17(S)-HETE
OPPIPPRXLIDJKN-LNRPRRCASA-N
17(S)-hydroxy-5(Z),8(Z),11(Z),14(Z)-eicosatetraenoic acid
5,8,11,14-Eicosatetraenoic acid, 17-hydroxy-, (5Z,8Z,11Z,14Z,17S)- | [Molecular Formula]
C20H32O3 | [MDL Number]
MFCD11113142 | [MOL File]
183509-25-3.mol | [Molecular Weight]
320.47 |
| Chemical Properties | Back Directory | [Boiling point ]
477.3±33.0 °C(Predicted) | [density ]
0.984±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
0.1 M Na2CO3: 2 mg/ml; DMF: Miscible; DMSO: Miscible; Ethanol: Miscible; PBS (pH 7.2): 0.8 mg/ml | [pka]
4.75±0.10(Predicted) |
| Hazard Information | Back Directory | [Uses]
17(S)-HETE is a cytochrome P450 (CYP450) metabolite of arachidonic acid. | [Definition]
ChEBI: 17(S)-HETE is a hydroxy fatty acid and a polyunsaturated fatty acid. | [in vivo]
17S-HETE (1-20 μg, i.a.) inhibits proximal tubule ATPase activity in New Zealand white rabbit[2]. | Animal Model: | New Zealand White rabbit[2] | | Dosage: | 1-20 μg | | Administration: | injection into artery | | Result: | Inhibited more than 70% ATPase activity at the concentration of 2 μM. |
| [IC 50]
CYP1B1 |
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