| Identification | Back Directory | [Name]
Cyanine3 maleimide | [CAS]
1838643-41-6 | [Synonyms]
Cyanine3 maleimide
Cyanine3 maleimide,Cy3 MAL | [Molecular Formula]
C36H43ClN4O3 | [MDL Number]
MFCD28385512 | [MOL File]
1838643-41-6.mol | [Molecular Weight]
615.22 |
| Chemical Properties | Back Directory | [solubility ]
Soluble in DMSO, DMF, DCM | [form ]
Solid | [color ]
Light yellow to brown | [Appearance]
red powder | [InChIKey]
WONAOVDQEMKIMH-UHFFFAOYSA-N | [SMILES]
C(N1C(C(C)(C)C2=CC=CC=C12)=CC=CC1C(C2=CC=CC=C2[N+]=1C)(C)C)CCCCC(=O)NCCN1C(C=CC1=O)=O.[Cl-] |
| Hazard Information | Back Directory | [Description]
Cy3 maleimide is a mono-reactive dye containing maleimide group, which can selectively and efficiently attach Cyanine3 fluorophore(an analog of Cy3?) to proteins and peptides containing cysteine residues, as well as to other thiolated molecules (such as thiol-containing oligonucleotides). Sulfo-Cy3 maleimide version is available for the labeling of antibodies and other sensitive proteins. | [Uses]
Cy3 maleimide chloride is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing maleimide functional groups. Cy3 is a fluorescent dye with a fluorescence spectrum typically in the green to orange wavelength range. The alkyne functional group of Cy3 maleimide chloride can undergo a "thiol-acrylamide" reaction with molecules containing sulfur-oxygen functional groups to form covalent bonds. Cy3 maleimide chloride can bind to biological molecules such as proteins and antibodies to track their location and dynamic changes in biological samples. | [Abs/Em Maxima]
555/570 nm | [Fluoresene quantum yield]
0.31 | [Extinction Coefficient]
150000 | [CF260]
0.04 | [CF280]
0.09 |
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