ChemicalBook--->CAS DataBase List--->184162-21-8

184162-21-8

184162-21-8 Structure

184162-21-8 Structure
IdentificationBack Directory
[Name]

SR142948
[CAS]

184162-21-8
[Synonyms]

SR142948A HCl
SR142948A hydrochloride
SR 142948 hydrochloride
SR 142948A >=98% (HPLC)
2-[[5-(2,6-dimethoxyphenyl)-1-(4-(N-(3-dimethylaminopropyl)-N-methylcarbamoyl)-2-isopropylphenyl)-1H-pyrazole3-carbonyl]amino] adamantane-2-carboxylic acid hydrochloride
[Molecular Formula]

C39H52ClN5O6
[MDL Number]

MFCD03106502
[MOL File]

184162-21-8.mol
[Molecular Weight]

722.32
Chemical PropertiesBack Directory
[storage temp. ]

2-8°C
[solubility ]

H2O: ≥2mg/mL at warmed to 60°C
[form ]

powder
[color ]

white to beige
Safety DataBack Directory
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

SR 142948A was used to study the role of neurotensin signaling in intracellular alkanization and expression of IL-8 in human pancreatic cancer cells.
[Definition]

ChEBI: 2-[[[5-(2,6-dimethoxyphenyl)-1-[4-[[3-(dimethylamino)propyl-methylamino]-oxomethyl]-2-propan-2-ylphenyl]-3-pyrazolyl]-oxomethyl]amino]-2-adamantanecarboxylic acid is a N-acyl-amino acid.
[Biochem/physiol Actions]

SR 142948A is a non-peptide Neurotensin receptor antagonist
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