| Identification | Back Directory | [Name]
Thieno[2,3-d]thiazole-5-carboxamide, 2-[4-[(dimethylamino)carbonyl]-1-piperidinyl]-N-(2-methyl-5-benzoxazolyl)- | [CAS]
1845720-46-8 | [Synonyms]
Antitubercular agent-26
Thieno[2,3-d]thiazole-5-carboxamide, 2-[4-[(dimethylamino)carbonyl]-1-piperidinyl]-N-(2-methyl-5-benzoxazolyl)- | [Molecular Formula]
C22H23N5O3S2 | [MOL File]
1845720-46-8.mol | [Molecular Weight]
469.58 |
| Hazard Information | Back Directory | [Uses]
Antitubercular agent-26 (Compound 32) is an orally active anti-tubercular agent with an extracellular IC50 of 0.50 μM and an intracellular IC50 of 0.51 μM against M. tuberculosis H37Rv. Antitubercular agent-26 shows good metabolic stability, low risk of cardiotoxicity and no genotoxicity[1]. | [References]
[1] Jin G, et al. Discovery of thienothiazolocarboxamide analogues as novel anti-tubercular agent. Bioorg Med Chem. 2020 Dec 1;28(23):115797. DOI:10.1016/j.bmc.2020.115797 |
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