| Chemical Properties | Back Directory | [solubility ]
DMF: Slightly Soluble
DMSO: Slightly Soluble | [form ]
Solid | [color ]
White to off-white | [Sequence]
Ac-Ala-Asn-Trp-Asn-Gly-Phe-Gly-Trp-Arg-Phe-NH2 |
| Hazard Information | Back Directory | [Uses]
Kisspeptin 234 TFA, is a 10 amino acid peptide as well as a kisspeptin receptor (KISS1, GPR54) antagonist. Kisspeptin 234 TFA is an analog of Kisspeptin 10[1]. | [in vivo]
Kisspeptin 234 (1 mg/kg, ip, daily, 28 days) TFA can inhibit the anti-fibrotic effect of Kisspeptin-13 in the bleomycin (BLM)-induced lung fibrosis model of C57BL/6 mice, especially in weight loss, decreased survival rate, increased lung coefficient, and massive infiltration[1].
| [References]
[1] Lei Z, et al. Kisspeptin?13 inhibits bleomycin?induced pulmonary fibrosis through GPR54 in mice. Mol Med Rep. 2019 Aug;20(2):1049-1056. DOI:10.3892/mmr.2019.10341 |
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