| Identification | Back Directory | [Name]
9,12-Octadecadienoic acid (9Z,12Z)-, 1,1',1'',1'''-[(3,6-dioxo-2,5-piperazinediyl)bis(4,1-butanediylnitrilodi-4,1-butanediyl)] ester | [CAS]
1853203-01-6 | [Synonyms]
9,12-Octadecadienoic acid (9Z,12Z)-, 1,1',1'',1'''-[(3,6-dioxo-2,5-piperazinediyl)bis(4,1-butanediylnitrilodi-4,1-butanediyl)] ester | [Molecular Formula]
C100H176N4O10 | [MOL File]
1853203-01-6.mol | [Molecular Weight]
1594.53 |
| Chemical Properties | Back Directory | [Boiling point ]
1239.1±65.0 °C(Predicted) | [density ]
0.959±0.06 g/cm3(Predicted) | [solubility ]
Ethanol: 10 mg/ml | [pka]
12.87±0.60(Predicted) |
| Hazard Information | Back Directory | [Description]
OF-C4-Deg-Lin is an ionizable cationic lipid.1 It has been used in the generation of lipid nanoparticles (LNPs) for the delivery of siRNA and mRNA in vitro and in vivo. Intravenous administration of LNPs containing OF-C4-Deg-Lin and encapsulating an mRNA reporter selectively accumulate in mouse spleen. | [Uses]
50-C2-C9-4tail has been used in the generation of lipid nanoparticles (LNPs) for the delivery of siRNA and mRNA in vitro and in vivo. | [References]
1. Fenton, O.S., Kauffman, K.J., McClellan, R.L., et al. Customizable lipid nanoparticle materials for the delivery of siRNAs and mRNAs Angew Chem. Int. Ed. Engl. 57(41),13582-13586(2018). |
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| Company Name: |
DC Chemicals
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021-58447131 13564518121 |
| Website: |
www.chemicalbook.com/showsupplierproductslist927327/0.htm |
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