ChemicalBook--->CAS DataBase List--->1854126-47-8

1854126-47-8

1854126-47-8 Structure

1854126-47-8 Structure
IdentificationBack Directory
[Name]

Hydroxychloroquine Sulfate EP Impurity C-d4 (Desethyl Hydroxy Chloroquine-d4)
[CAS]

1854126-47-8
[Synonyms]

HydroxychloroquineSulfateEPImpurityC-d4
Hydroxychloroquine Sulfate EP Impurity C-d4 (Desethyl Hydroxy Chloroquine-d4)
[Molecular Formula]

C16H22ClN3O
[MOL File]

1854126-47-8.mol
[Molecular Weight]

307.82
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

DMF: Soluble,DMSO: Soluble,Methanol: Soluble
[form ]

A solid
Hazard InformationBack Directory
[Biological Activity]

Desethyl hydroxychloroquine-d4 is intended for use as an internal standard for the quantification of desethyl hydroxychloroquine by GC- or LC-MS. Desethyl hydroxychloroquine is an active metabolite of hydroxychloroquine .1 It is formed via the desethylation of hydroxychloroquine in the liver, a process mediated by the cytochrome P450 (CYP) isoforms CYP2D6, CYP3A4, CYP3A5, and CYP2C8.
[storage]

Store at -20°C
[References]

1.Charlier, B., Pingeon, M., Dal Piaz, F., et al.Development of a novel ion-pairing HPLC-FL method for the separation and quantification of hydroxychloroquine and its metabolites in whole bloodBiomed. Chromatogr.32(8)e4258(2018)
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