ChemicalBook--->CAS DataBase List--->185669-79-8

185669-79-8

Request For Quotation
185669-79-8 Structure

185669-79-8 Structure
IdentificationBack Directory
[Name]

CHEMBRDG-BB 5552132
[CAS]

185669-79-8
[Synonyms]

CHEMBRDG-BB 5552132
(4-METHOXYBENZYL)(1-NAPHTHYLMETHYL)AMINE
N-(4-Methoxybenzyl)-1-(naphthalen-1-yl)MethanaMine
N-[(4-Methoxyphenyl)methyl]-1-naphthalenemethanamine
1-Naphthalenemethanamine, N-[(4-methoxyphenyl)methyl]-
(4-Methoxyphenyl)-N-(naphthalen-1-ylMethyl)MethanaMine
(4-methoxybenzyl)(1-naphthylmethyl)amine(SALTDATA: HBr)
(4-Methoxyphenyl)-N-(naphthalen-1-ylMethyl)MethanaMine hcl
[Molecular Formula]

C19H19NO
[MDL Number]

MFCD01469095
[MOL File]

185669-79-8.mol
[Molecular Weight]

277.36
Chemical PropertiesBack Directory
[storage temp. ]

under inert gas (nitrogen or Argon) at 2–8 °C
[solubility ]

DMSO: 10mg/mL, clear, colorless
[form ]

solid
[color ]

white
[InChI]

1S/C19H19NO/c1-21-18-11-9-15(10-12-18)13-20-14-17-7-4-6-16-5-2-3-8-19(16)17/h2-12,20H,13-14H2,1H3
[InChIKey]

GIFYKGIODMXYNT-UHFFFAOYSA-N
[SMILES]

COC(C=C1)=CC=C1CNCC2=C(C=CC=C3)C3=CC=C2
Safety DataBack Directory
[Symbol(GHS) ]

Corrosion (GHS05)Environment (GHS09)
GHS05,GHS09
[Signal word ]

Warning
[Hazard statements ]

H413
[Precautionary statements ]

P501-P273
[WGK Germany ]

WGK 2
[Storage Class]

11 - Combustible Solids
Hazard InformationBack Directory
[Uses]

A cell-permeable, renal outer medullary potassium (ROMK) blocker that is shown to inhibit inward rectifier potassium channel, Kir2.1 (IC50 = 1.8 µM and 290 nM, at pH 7.4 and pH 8.5, respectively). It exhibits little selectivity against other members of the Kir2.x family, but has no effect on Kir1.1 (IC50 >300 µM) and displays weak activity for Kir4.1 and Kir7.1 (IC50 = 76 µM and 33 µM, respectively). It is reported to be assayed in 218 MLPCN HTS campaigns, demonstrating activity in only two assays that are not based on Kir2.1. Furthermore, it displays a relatively clean profile in a radioligand binding panel of 68 GPCRs, ion channels and transporters.
[Definition]

ChEBI: 1-(4-methoxyphenyl)-N-(1-naphthalenylmethyl)methanamine is a member of naphthalenes.
185669-79-8 suppliers list
Company Name: J & K SCIENTIFIC LTD.  
Telephone: 18210857532 18210857532
Website: https://www.jkchemical.com
Company Name: Nanjing Norris-Pharm Technology Co., Ltd  
Telephone: 13901585132
Website:
Company Name: Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd.  
Telephone: +86-28-85122536 85324413
Website: www.chemicalbook.com/ShowSupplierProductsList12313/0_EN.htm
Company Name: CEG Chemical Science&Technology Co., Ltd.  
Telephone: Mobile:13665161512
Website: www.cegchemical.com
Company Name: Shanghai YuanYe Biotechnology Co., Ltd.  
Telephone: 18916372613
Website: www.shyuanye.com
Company Name: Amadis Chemical Company Limited  
Telephone: 571-89925085
Website: http://www.amadischem.com
Company Name: Aikon International Limited  
Telephone: 025-66113011 19370895928
Website: www.aikonchem.com
Company Name: Wuxi Donghe Pharmaceutical Technology Co., Ltd.  
Telephone: 63313187 15358055255
Website: http://www.cegchemical.com
Company Name: Nantong puyue biomedical Co., Ltd  
Telephone: 0513-0513-0513-89158300 18014392889
Website: http://www.puyerbiopharma.com
Company Name: Energy Chemical  
Telephone: 400-0056266
Website: www.energy-chemical.com
Company Name: Jinan Jiuli Biotechnology Co. , Ltd.  
Telephone: 15865264761
Website: www.chemicalbook.com/ShowSupplierProductsList89365/0_EN.htm
Company Name: Bide Pharmatech Ltd.  
Telephone: 400-6005915
Website: www.picasso-e.com/
Company Name: Hefei Mokai Pharmaceutical Technology Co., Ltd  
Telephone: 18130062233
Website: www.yxjchem.com/
Company Name: Shanghai Aladdin Biochemical Technology Co.,Ltd.  
Telephone: 6206333 13167063860
Website: www.aladdin-e.com/
Company Name: Hangzhou MolCore BioPharmatech Co.,Ltd.  
Telephone: +86-057181025280; +8617767106207
Website: https://www.molcore.com/
Tags:185669-79-8 Related Product Information
448947-81-7 126150-97-8 298-46-4