ChemicalBook--->CAS DataBase List--->186000-41-9

186000-41-9

186000-41-9 Structure

186000-41-9 Structure
IdentificationBack Directory
[Name]

2-FLUOROPHENYLZINC IODIDE
[CAS]

186000-41-9
[Synonyms]

2-FLUOROPHENYLZINC IODIDE
2-fluorophenylzinc iodide solution
2-FLUOROPHENYLZINC IODIDE, 0.5M SOLN IN
2-Fluorophenylzinc iodide solution 0.5 in THF
2-FLUOROPHENYLZINC IODIDE ISO 9001:2015 REACH
2-Fluorophenylzinc iodide solution 0.5M in THF
2-Fluorophenylzinc iodide 0.5 M in Tetrahydrofuran
2-Fluorophenylzinc iodide, Packaged under Argon in resealable ChemSeal? bottles
2-Fluorophenylzinc iodide, 0.5M in THF, packaged under Argon in resealable CheMSeal^t bottles
[Molecular Formula]

C6H4FIZn
[MDL Number]

MFCD02260162
[MOL File]

186000-41-9.mol
[Molecular Weight]

287.39
Chemical PropertiesBack Directory
[Boiling point ]

65 °C
[density ]

1.03 g/mL at 25 °C
[Fp ]

1 °F
[storage temp. ]

2-8°C
[Sensitive ]

Air Sensitive
[Exposure limits]

ACGIH: TWA 50 ppm; STEL 100 ppm (Skin)
OSHA: TWA 200 ppm(590 mg/m3)
NIOSH: IDLH 2000 ppm; TWA 200 ppm(590 mg/m3); STEL 250 ppm(735 mg/m3)
Questions And AnswerBack Directory
[Uses]

2-Fluorophenyl zinc iodide is a pharmaceutical intermediate that has been reported in the literature to be used in the preparation of cannabinoid receptor modulators and estrogen receptor β (ERβ) agonists.
[Application]

2-Fluorophenyl zinc iodide can be used to prepare cannabinoid receptor modulators with the following structures. Currently recognized cannabinoid receptors include CB1 and CB2 receptors. In the early 1990s, CB1 and CB2 receptors, which bind to cannabinoids in vivo, were cloned, respectively. The CB1 receptor consists of 473 amino acids and 7 transmembrane domains, while the CB2 receptor consists of 360 amino acids and 7 transmembrane domains; both are G protein-coupled receptors. Cannabinoid receptor modulators have shown good therapeutic effects in treating multiple sclerosis, pain, and liver fibrosis.
Safety DataBack Directory
[Symbol(GHS) ]


GHS05,GHS02,GHS07,GHS08
[Signal word ]

Danger
[Hazard statements ]

H225-H302-H319-H335-H351-H261-H314-H318-H333
[Precautionary statements ]

P210-P280-P301+P312+P330-P305+P351+P338-P370+P378-P403+P235-P223-P303+P361+P353-P405-P501a
[Hazard Codes ]

F,Xn
[Risk Statements ]

11-14-19-22-36/37/38-40-36/37
[Safety Statements ]

16-26-33-36/37
[RIDADR ]

UN 2056 3/PG 2
[WGK Germany ]

1
[Hazard Note ]

Flammable
[HazardClass ]

4.3
[HS Code ]

2827590000
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