ChemicalBook--->CAS DataBase List--->186204-33-1

186204-33-1

186204-33-1 Structure

186204-33-1 Structure
IdentificationBack Directory
[Name]

Lurasidone metabolite 14326
[CAS]

186204-33-1
[Synonyms]

5α/6α-Hydroxy Lurasidone
Lurasidone metabolite 14326
Lurasidone Inactive Metabolite 14326, 5β/6β-Hydroxy Lurasidone Hydrochloride (Mixture of Diastereomers)
4,7-Methano-1H-isoindole-1,3(2H)-dione, 2-[[(1R,2R)-2-[[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]methyl]cyclohexyl]methyl]hexahydro-5-hydroxy-, (3aR,4S,5S,7S,7aS)-rel-
[Molecular Formula]

C28H36N4O3S
[MDL Number]

MFCD28900718
[MOL File]

186204-33-1.mol
[Molecular Weight]

508.68
Chemical PropertiesBack Directory
[Boiling point ]

658.2±55.0 °C(Predicted)
[density ]

1.325±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

Chloroform: soluble
[form ]

A solid
[pka]

14.69±0.20(Predicted)
Hazard InformationBack Directory
[Description]

Lurasidone metabolite 14326 is an active metabolite of the atypical antipsychotic lurasidone .
[Uses]

5α/6α-Hydroxy Lurasidone was used in preparation of cyclic imide derivatives as psychotropics. It is a metabolite of Lurasidone (L474920), which is a antipsychotic compound.
[storage]

Store at -20°C
[References]

[1] WILLIAM M GREENBERG L C. Pharmacokinetics and Pharmacodynamics of Lurasidone Hydrochloride, a Second-Generation Antipsychotic: A Systematic Review of the Published Literature.[J]. Clinical Pharmacokinetics, 2017, 56 1: 493-503. DOI: 10.1007/s40262-016-0465-5
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