| Identification | Back Directory | [Name]
CY2-SE | [CAS]
186205-33-4 | [Synonyms]
CY2-SE
CY2-SE, BR
Cy2-SE (iodine)
Cyanine2 Succinimidyl Ester
2-((1E,3E)-3-(3-(6-((2,5-DIOXOPYRROLIDIN-1-YL)OXY)-6-OXOHEXYL)BENZO[D]OXAZOL-2(3H)-YLIDENE)PROP-1-EN-1-YL)-3-ETHYLBENZO[D]OXAZOL-3-IUM IODIDE | [Molecular Formula]
C29H30IN3O6 | [MDL Number]
MFCD29472246 | [MOL File]
186205-33-4.mol | [Molecular Weight]
643.48 |
| Chemical Properties | Back Directory | [solubility ]
DMF: 30 mg/ml; DMF:PBS (pH 7.2) (1:1): 0.50 mg/ml; DMSO: 10 mg/ml; Ethanol: slightly soluble; PBS (pH 7.2): slightly soluble | [form ]
A crystalline solid | [color ]
Orange to red | [Appearance]
Orange solid | [ex/em]
484/504nm (PBS/ethanol mixture) | [ε(extinction coefficient)]
150000 L⋅mol−1⋅cm−1 | [Φ(quantum yield)]
0.12 |
| Hazard Information | Back Directory | [Chemical Properties]
Appearance: Orange-red solid
ex/em: 484/504nm (PBS/ethanol mixture)
Extinction coefficient (ε): 150000 L??mol??1??cm??1
Quantum yield (Φ): 0.12 | [Uses]
Cy2-SE iodine is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis[1]. CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance[2]. | [References]
[1] Ptaszek M. Rational design of fluorophores for in vivo applications. Prog Mol Biol Transl Sci. 2013;113:59-108. DOI:10.1016/B978-0-12-386932-6.00003-X
[2] Shindy, H. A. (2017). Fundamentals in the chemistry of cyanine dyes: A review. Dyes and Pigments, 145, 505–513. doi:10.1016/j.dyepig.2017.06.029 |
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