| Identification | Back Directory | [Name]
4-Quinazolinemethanol, α-(4-methoxyphenyl)-α-methyl- | [CAS]
187336-16-9 | [Synonyms]
PVHD121
4-Quinazolinemethanol, α-(4-methoxyphenyl)-α-methyl- | [Molecular Formula]
C17H16N2O2 | [MOL File]
187336-16-9.mol | [Molecular Weight]
280.33 |
| Chemical Properties | Back Directory | [Boiling point ]
477.4±40.0 °C(Predicted) | [density ]
1.228±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
DMSO: 2mg/mL, clear | [form ]
powder | [pka]
12.73±0.29(Predicted) | [color ]
white to beige |
| Hazard Information | Back Directory | [Biological Activity]
PVHD121 is potent antimitotic agent th at binds to the colchicine site of tubulin. PVHD121 selectively inhibits microtubule formation at centrosomes during mitosis. It delays entry into mitosis causing long lasting mitotic arrest by activation of spindle checkpoint. |
|
| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
|