| Identification | Back Directory | [Name]
L-Leucine, L-valyl-L-tyrosyl-L-α-aspartyl-L-phenylalanyl-L-phenylalanyl-L-valyl-L-tryptophyl- | [CAS]
187671-49-4 | [Synonyms]
Tyrosinase-related Protein 2 (TRP-2) (181-188)
L-Leucine, L-valyl-L-tyrosyl-L-α-aspartyl-L-phenylalanyl-L-phenylalanyl-L-valyl-L-tryptophyl- | [Molecular Formula]
C58H73N9O12 | [MOL File]
187671-49-4.mol | [Molecular Weight]
1088.27 |
| Chemical Properties | Back Directory | [Boiling point ]
1451.5±65.0 °C(Predicted) | [density ]
1.281±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
3.40±0.10(Predicted) | [color ]
White to off-white | [Sequence]
Val-Tyr-Asp-Phe-Phe-Val-Trp-Leu |
| Hazard Information | Back Directory | [Uses]
Tyrosinase-related Protein 2 (TRP-2) (181-188) is a tyrosinase-related protein 2 (TRP-2)-derived peptide, corresponding to residues 180-188. Tyrosinase-related Protein 2 (TRP-2) (181-188) is the major reactive epitope within TRP-2 recognized by anti-B16 CTLs. Tyrosinase-related Protein 2 (TRP-2) (181-188) is a peptide conforming to the MHC class I H2-Kb?binding motif[1]. | [References]
[1] M B Bloom, et al. Identification of tyrosinase-related protein 2 as a tumor rejection antigen for the B16 melanoma. J Exp Med. 1997 Feb 3;185(3):453-9. DOI:10.1084/jem.185.3.453 |
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