| Identification | Back Directory | [Name]
2-BUTYL-3,4-DIHYDRO-N,N-DIMETHYL-4-OXO-3-[[2'-(1H-TETRAZOL-5-YL)[1,1'-BIPHENYL-4-YL]METHYL]]-5H-IMIDAZO[4,5-C]PYRIDINE-5-ACETAMIDE HYDROCHLORIDE | [CAS]
187683-79-0 | [Synonyms]
EMD 66684
2-BUTYL-3,4-DIHYDRO-N,N-DIMETHYL-4-OXO-3-[[2'-(1H-TETRAZOL-5-YL)[1,1'-BIPHENYL-4-YL]METHYL]]-5H-IMIDAZO[4,5-C]PYRIDINE-5-ACETAMIDE HYDROCHLORIDE | [Molecular Formula]
C28H31KN8O2 | [MDL Number]
MFCD08703087 | [MOL File]
187683-79-0.mol | [Molecular Weight]
550.71 |
| Hazard Information | Back Directory | [Uses]
EMD 66684 is a useful intermediate. | [Biological Activity]
Highly potent and very selective non-peptide angiotensin AT 1 receptor antagonist (IC 50 values are 0.7 and > 10000 nM for AT 1 and AT 2 receptors respectively). Potently inhibits angiotensin II-induced contractions in isolated rabbit aorta (IC 50 = 0.2 nM) and reduces blood pressure in hypertensive rats. |
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Alomone Labs
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