| Chemical Properties | Back Directory | [Boiling point ]
2669.2±65.0 °C(Predicted) | [density ]
1.231±0.06 g/cm3(Predicted) | [form ]
Solid | [color ]
White to off-white | [Sequence]
Trp-Glu-Ala-Lys-Leu-Ala-Lys-Ala-Leu-Ala-Lys-Ala-Leu-Ala-Lys-His-Leu-Ala-Lys-Ala-Leu-Ala-Lys-Ala-Leu-Lys-Ala-Cys-Glu-Ala |
| Hazard Information | Back Directory | [Uses]
KALA is an amphiphilic peptide that forms an α-helical structure at physiological pH. KALA modifies a plasmid DNA-encapsulating liposomal membrane and is used as a fusogenic peptide in order to achieve effective liver targeting and transfection of DNA via galactose receptors[1]. | [References]
[1] Naoya Miura, et al. Identification and Evaluation of the Minimum Unit of a KALA Peptide Required for Gene Delivery and Immune Activation. J Pharm Sci. 2017 Oct;106(10):3113-3119. DOI:10.1016/j.xphs.2017.05.014 |
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