| Identification | Back Directory | [Name]
- | [CAS]
1883512-27-3 | [Synonyms]
endo BCN-PEG3-NH2
BCN-endo-PEG3-NH2
endo-BCN-PEG3-amine
BCN-PEG3-AMINE (ENDO) | [Molecular Formula]
C19H32N2O5 | [MDL Number]
MFCD32693308 | [MOL File]
1883512-27-3.mol | [Molecular Weight]
368.47 |
| Chemical Properties | Back Directory | [Boiling point ]
519.6±40.0 °C(Predicted) | [density ]
1.14±0.1 g/cm3(Predicted) | [storage temp. ]
-20°C, sealed storage, away from moisture and light | [form ]
Oil | [pka]
12.05±0.46(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Description]
endo-BCN-PEG3-amine is a click chemistry linker containing a BCN and an amine group. The BCN group can react with azide-tagged biomolecules under mile condition. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. | [Uses]
endo-BCN-PEG3-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. endo-BCN-PEG3-NH2 is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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| Company Name: |
csynbio
|
| Telephone: |
15051477682 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList1949820/0_EN.htm |
| Company Name: |
Bide Pharmatech Ltd.
|
| Telephone: |
400-1647117 13681763483 |
| Website: |
https://www.bidepharm.com/ |
|