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1883548-85-3

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1883548-85-3 Structure

1883548-85-3 Structure

Identification	Back Directory
[Name] 1-[(6-Chloroimidazo[2,1-b]thiazol-5-yl)sulfonyl]-1H-indole-3-ethanamine oxalate
[CAS] 1883548-85-3
[Synonyms] WAY 181187 oxalate 1-[(6-Chloroimidazo[2,1-b]thiazol-5-yl)sulfonyl]-1H-indole-3-ethanamine oxalate
[Molecular Formula] C17H15ClN4O6S2
[MDL Number] MFCD30182323
[MOL File] 1883548-85-3.mol
[Molecular Weight] 470.907

Chemical Properties	Back Directory
[storage temp. ] Store at -20°C
[solubility ] Soluble in DMSO

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[Uses] WAY 181187 Oxalate is a high affinity and selective 5-HT6 agonist. It displays 60-fold selectivity over other 5-HT and monoamine receptors and increases firing rate of 5-HT neurons.
[in vivo] Acute administration of WAY-181187 (SAX-187) oxalate (3-30 mg/kg, s.c.) significantly increases extracellular GABA concentrations without altering the levels of glutamate or norepinephrine in the rat frontal cortex. Additionally, WAY-181187 oxalate (30 mg/kg, s.c.) produces modest yet significant decreases in cortical dopamine and 5-HT levels^[1].
[IC 50] 5-HT₆ Receptor: 2.2 nM (Ki); 5-HT₆ Receptor: 6.6 nM (EC₅₀)
[storage] Store at -20°C

1883548-85-3 suppliers list

Company Name:	Shanghai Hongye Biotechnology Co. Ltd
Telephone:	400-9205774 400-920-5774
Website:	www.glpbio.cn

Company Name:	TargetMol Chemicals Inc.
Telephone:	15002134094
Website:	https://www.targetmol.cn/

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