| Chemical Properties | Back Directory | [Boiling point ]
571.3±60.0 °C(Predicted) | [density ]
1.27±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [pka]
4.33±0.50(Predicted) |
| Hazard Information | Back Directory | [Uses]
JTP-103237 is a MGAT2 inhibitor (IC50: 0.019 μM and 6.423 μM for hMGAT2 and hMGAT3 respectively). JTP-103237 modulates fat absorption, decreases plasma glucose levels and prevents diet-induced obesity[1]. | [storage]
Store at -20°C | [References]
[1] Okuma C, et al. JTP-103237, a novel monoacylglycerol acyltransferase inhibitor, modulates fat absorption and prevents diet-induced obesity. Eur J Pharmacol. 2015 Jul 5;758:72-81. DOI:10.1016/j.ejphar.2015.03.072 |
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