| Identification | Back Directory | [Name]
Octanoic acid, 8-[3-methoxy-5-[(1E)-2-(4-methoxyphenyl)ethenyl]phenoxy]- | [CAS]
1891020-45-3 | [Synonyms]
Octanoic acid, 8-[3-methoxy-5-[(1E)-2-(4-methoxyphenyl)ethenyl]phenoxy]- | [Molecular Formula]
C24H30O5 | [MOL File]
1891020-45-3.mol | [Molecular Weight]
398.49 |
| Chemical Properties | Back Directory | [Boiling point ]
594.8±50.0 °C(Predicted) | [density ]
1.123±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
DMSO: 2mg/mL, clear | [form ]
powder | [pka]
4.77±0.10(Predicted) | [color ]
white to beige |
| Hazard Information | Back Directory | [Biological Activity]
RLA8 is an orally available and potent agonist of peroxisome proliferator-activated receptors (PPARs)-α/γ/δ and G-protein-coupled receptor 40 (GPR40). RLA8 reverses the proregression of pathological changes such as hepatic lipid accumulationsteatosisinflammation and fibrosis in mice models of nonalcoholic steatohepatitis (NASH). Alsoit improves serum HDL cholesterolreduce hepatic free fatty acid and triglyceride levelsand alleviate insulin resistance. |
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| Company Name: |
Merck KGaA
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| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
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