| Identification | Back Directory | [Name]
(5R,10S)-10,11-Dihydro-3,7,8-trimethoxy-12-methyl-10,5-(iminomethano)-5H-dibenzo[a,d]cyclohepten-2-ol | [CAS]
18927-72-5 | [Synonyms]
Thalisopavine
(5R,10S)-10,11-Dihydro-3,7,8-trimethoxy-12-methyl-10,5-(iminomethano)-5H-dibenzo[a,d]cyclohepten-2-ol
10,5-(Iminomethano)-5H-dibenzo[a,d]cyclohepten-2-ol, 10,11-dihydro-3,7,8-trimethoxy-12-methyl-, (5R)- (9CI) | [Molecular Formula]
C20H23NO4 | [MOL File]
18927-72-5.mol | [Molecular Weight]
341.4 |
| Chemical Properties | Back Directory | [Melting point ]
211-2°C | [Boiling point ]
471.011±45.00 °C(Press: 760.00 Torr)(predicted) | [density ]
1.212±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [pka]
10.080±0.20(predicted) |
| Hazard Information | Back Directory | [Description]
This alkaloid has been isolated from the roots of Thalictrum dasycarpum
Fisch. et al. It crystallizes as colourless rods from Et20 or needles from EtOH.
It has a specific rotation of[α]25D - 210° (c 0.21, CHCI3) and gives an ultraviolet spectrum in EtOH with a single absorption maximum at 289 nm. The
methyl ether forms needles from Et20-EtOH with m.p. 91-2°C. The structure
has been proved by total synthesis of the base. | [References]
Kupchan, Yoshitaka,J. Org. Chem., 34,1062 (1969) |
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