| Identification | Back Directory | [Name]
Epoxycytochalasin C, 19,20- | [CAS]
189351-79-9 | [Synonyms]
19,20-Epoxycytochalasin C
Epoxycytochalasin C, 19,20- | [Molecular Formula]
C30H37NO7 | [MDL Number]
MFCD14635373 | [MOL File]
189351-79-9.mol | [Molecular Weight]
523.63 |
| Chemical Properties | Back Directory | [Boiling point ]
737.4±60.0 °C(Predicted) | [density ]
1.30±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble | [form ]
A powder | [pka]
12.00±0.70(Predicted) |
| Hazard Information | Back Directory | [Uses]
19,20-Epoxycytochalasin C is a cytotoxic cytochalasin. | [Uses]
19,20-Epoxycytochalasin C is a major component of the cytochalasin complex. Although reported in the literature, there is no available biological data on the metabolite other than in-house data suggesting the presence of the epoxide renders the metabolite more active than cytochalasin C in inhibition of tumour cell growth in vitro. | [in vivo]
Evaluation of in vivo antimalarial activity of 19,20-Epoxycytochalasin C in a mouse model at 100 mg/kg dose shows that this compound has weak suppressive antiplasmodial activity and is toxic to animals[1]. | [IC 50]
Plasmodium; Microbial Metabolite |
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