ChemicalBook--->CAS DataBase List--->189684-49-9

189684-49-9

189684-49-9 Structure

189684-49-9 Structure
IdentificationBack Directory
[Name]

AC-LEU-GLU-VAL-ASP-PNA
[CAS]

189684-49-9
[Synonyms]

AC-LEVD-PNA
AC-LEU-GLU-VAL-ASP-PNA
CASPASE-4 SUBSTRATE (AFC)
CASPASE-4 SUBSTRATE (CHROMOGENIC)
AC-LEU-GLU-VAL-ASP-PARANITROANILIDE
CASPASE 4 (ICH-2) SUBSTRATE 1, CHROMOGENIC
[Molecular Formula]

C28H40N6O11
[MDL Number]

MFCD01631265
[MOL File]

189684-49-9.mol
[Molecular Weight]

636.65
Chemical PropertiesBack Directory
[Boiling point ]

1086.614±65.00 °C(Press: 760.00 Torr)(predicted)
[density ]

1.327±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
[form ]

Solid
[pka]

4.035±0.10(predicted)
[color ]

White to off-white
[Sequence]

Ac-Leu-Glu-Val-Asp-{pNA}
Hazard InformationBack Directory
[Uses]

Ac-LEVD-pNA is a chromogenic substrate for caspase-4 and can be used to detect caspase-4 activity[1].
[References]

[1] Arduíno DM, et al. Endoplasmic reticulum and mitochondria interplay mediates apoptotic cell death: relevance to Parkinson's disease. Neurochem Int. 2009 Sep;55(5):341-8. DOI:10.1016/j.neuint.2009.04.004
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