| Identification | Back Directory | [Name]
ABT 491 | [CAS]
189689-94-9 | [Synonyms]
ABT 491
PAF Receptor Antagonist, ABT-491
ABT-491 hydrochloride >=98% (HPLC)
PAF Receptor Antagonist, ABT-491 - CAS 189689-94-9 - Calbiochem
A-137491, 4-Ethynyl-N,N-dimethyl-3-[3-fluoro-4-[(2-methyl-1H-imidazo-[4,5-c]pyridin-1-yl)methyl]benzoyl]-1H-indole-1-carboxamide hydrochloride | [Molecular Formula]
C28H22FN5O2.ClH | [MDL Number]
MFCD00945301 | [MOL File]
189689-94-9.mol | [Molecular Weight]
515.974 |
| Chemical Properties | Back Directory | [Melting point ]
170-178 °C(lit.) | [storage temp. ]
2-8°C | [solubility ]
H2O: 22 mg/mL, freely soluble | [form ]
Off-white solid | [color ]
white | [Water Solubility ]
water: 10mg/mL | [InChI]
1S/C28H22FN5O2.ClH/c1-5-18-7-6-8-25-26(18)21(16-34(25)28(36)32(3)4)27(35)19-9-10-20(22(29)13-19)15-33-17(2)31-23-14-30-12-11-24(23)33;/h1,6-14,16H,15H2,2-4H3;1H | [InChIKey]
AWRGBOKANQBIBM-UHFFFAOYSA-N | [SMILES]
Cl[H].CN(C)C(=O)n1cc(C(=O)c2ccc(Cn3c(C)nc4cnccc34)c(F)c2)c5c(cccc15)C#C |
| Hazard Information | Back Directory | [Biochem/physiol Actions]
Highly potent, selective and orally active platelet-activating factor (PAF) receptor antagonist. Ki = 0.6 nM in human platelets. |
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