| Identification | Back Directory | [Name]
1H-PYRROLO[2,3-B]PYRIDINE-6-CARBONITRILE | [CAS]
189882-33-5 | [Synonyms]
6-CYANO-7-AZAINDOLE
7-Azaindole-6-carbonitrile
6-Cyano-1H-pyrrolo[2,3-b]pyridine
PYRROLO[2,3-B]PYRIDINE-6-CARBONITRILE
1H-PYRROLO[2,3-B]PYRIDINE-6-CARBONITRILE
1H-Pyrrolo[2,3-b]pyridine-6-carbonitrile(9CI)
1H-PYRROLO[2,3-B]PYRIDINE-6-CARBONITRILE ISO 9001：2015 REACH | [EINECS(EC#)]
251-156-6 | [Molecular Formula]
C8H5N3 | [MDL Number]
MFCD06659673 | [MOL File]
189882-33-5.mol | [Molecular Weight]
143.15 |
| Chemical Properties | Back Directory | [Melting point ]
187.4 °C | [Boiling point ]
463.9±28.0 °C(Predicted) | [density ]
1.29±0.1 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,2-8°C | [pka]
6.56±0.40(Predicted) |
| Hazard Information | Back Directory | [Chemical Properties]
Class white powder | [Description]
7-Azaindole, as a bioisostere of indole or purine, is widely used in drug development. Among them, 1H-pyrrolo[2,3-b]pyridine-6-carbonitrile is a key intermediate for the synthesis of a class of selective cyclin-dependent kinase (CDK) 7 inhibitors. Among mammalian CDKs, CDK7 has a unique integrated kinase activity that helps regulate the cell cycle and gene transcription. 1H-pyrrolo[2,3-b]pyridine-6-carbonitrile can be prepared using 7-azaindole-7-oxide as a raw material.
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| Company Name: |
Maya High Purity Chemicals
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| Telephone: |
+86 (573) 82222445 (0)18006601000 452520369 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList15221/0_EN.htm |
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