| Identification | Back Directory | [Name]
C6 L-erythro Ceramide (d18:1/6:0) | [CAS]
189894-78-8 | [Synonyms]
Hexanoyl-L-erythro-sphingosine
C6 L-erythro Ceramide (d18:1/6:0) | [Molecular Formula]
C24H47NO3 | [MOL File]
189894-78-8.mol | [Molecular Weight]
397.63 |
| Hazard Information | Back Directory | [Description]
C6 L-erythro Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides.1,2 It is metabolized by ceramide glucosyltransferase to form C6 L-erythro glucosylceramide. C6 L-erythro Ceramide is cytotoxic to U937 cells (IC50 = 18 μM).3
| [References]
1. Schwarz, A., and Futerman, A.H. Distinct roles for ceramide and glucosylceramide at different stages of neuronal growth J. Neurosci. 17(9),2929-2938(1997).
2. Paul, P., Kamisaka, Y., Marks, D.L., et al. Purification and characterization of UDP-glucose: Ceramide glucosyltransferase from rat liver Golgi membranes Curr. Opin. Struct. Biol. 271(4),2287-2293(1996).
3. Chang, Y.-T., Choi, J., Ding, S., et al. The synthesis and biological characterization of a ceramide library J. Am. Chem. Soc. 124(9),1856-1857(2002). |
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| Company Name: |
Alfa Chemistry
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| Tel: |
1-516-6625404 |
| Website: |
https://www.alfa-chemistry.com |
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