| Identification | Back Directory | [Name]
AC-DEVD-PNA | [CAS]
189950-66-1 | [Synonyms]
AC-DEVD-P
AC-DEVD-PNA
(2S,5S,8S,11S)
ACETYL-DEVD-PNA
AC-DEVD-PNA?, >98%
-11-(carboxymethyl)
-8-(2-carboxyethyl)
AC-ASP-GLU-VAL-ASP-PNA
-2-(2-Amino-2-oxoethyl)
N-Ac-Asp-Glu-Val-Asp-pNA
-5-isopropyl-3-(4-nitrophenyl)
Ac-DEVD-pNA(Caspase-3 Substrate)
AC-ASP-GLU-VAL-ASP-P-NITROANILIDE
CASPASE-3 SUBSTRATE (CHROMOGENIC)
CASPASE-3 SUBSTRATE I, COLORIMETRIC
AC-ASP-GLU-VAL-ASP-PNA: AC-DEVD-PNA
AC-ASP-GLU-VAL-ASP-PARANITROANILIDE
CASPASE 3/CPP32 CHROMOGENIC SUBSTRATE
ACETYL-ASP-GLU-VAL-ASP-(P-NITROANILIDE)
N-ACETYL-ASP-GLU-VAL-ASP-P-NITROANILIDE
N-ACETYL-ASP-GLU-VAL-ASP-P-NITROANILIDE PNA
CHROMOGENIC CASPASE 3 SUBSTRATE AC-DEVD-PNA
CASPASE 3 (APOPAIN) SUBSTRATE 1, CHROMOGENIC
Ac-DEVD-pNA，N-Acetyl-Asp-Glu-Val-Asp-p-Nitroanilide
CASPASE-3 SUBSTRATE VIII, WATER-SOLUBLE, COLORIMETRIC
Ac-DEVD-pNA,N-Acetyl-Asp-Glu-Val-Asp-p-Nitroanilide, >98%
-4,7,10,13-tetraoxo-3,6,9,12-tetraazatetradecan-1-oic acid
Ac-DEVD-pNA，Ac-Asp-Glu-Val-Asp-pNA，Ac-Asp-Glu-Val-Asp-p-nitroanilide
N-Acetyl-L-α-aspartyl-L-α-glutamyl-L-valyl-N-(4-nitrophenyl)-L-asparagine
N-Acetyl-L-a-aspartyl-L-a-glutamyl-L-valyl-N-(4-nitrophenyl)-L-asparagine
L-Asparagine, N-acetyl-L-α-aspartyl-L-α-glutamyl-L-valyl-N-(4-nitrophenyl)- (9CI) | [Molecular Formula]
C26H34N6O13 | [MDL Number]
MFCD00792707 | [MOL File]
189950-66-1.mol | [Molecular Weight]
638.58 |
| Chemical Properties | Back Directory | [Boiling point ]
1191.1±65.0 °C(Predicted) | [density ]
1.448±0.06 g/cm3(Predicted) | [storage temp. ]
−20°C
| [solubility ]
DMSO (Slightly), Methanol (Slightly, Heated) | [form ]
powder
| [pka]
2.97±0.10(Predicted) | [color ]
white
| [Water Solubility ]
Soluble in water (partly), dimethyl sulfoxide, buffer, pH 7, and acetonitrile:methanol (1:1) (1 mg/ml). | [Sequence]
N-Acetyl-Asp-Glu-Val-Asp-p-Nitroanilide | [Stability:]
Hygroscopic | [InChIKey]
GGXRLUDNGFFUKI-ORGXJRBJSA-N | [SMILES]
CC(C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(C)=O)C(=O)N[C@@H](CC(O)=O)C(=O)Nc1ccc(cc1)[N+]([O-])=O |
| Hazard Information | Back Directory | [Uses]
N-Acetyl-L-α-aspartyl-L-α-glutamyl-L-valyl-N-(4-nitrophenyl)-L-asparagine is an para-nitro aniline chromophore cleaved by caspase. | [Biochem/physiol Actions]
Colorimetric substrate for caspase 3, a protease that is rapidly activated when cells are exposed to apoptotic conditions and that cleaves poly(ADP-ribose) polymerase. | [IC 50]
Caspase-3; Caspase-7 |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Sigma-Aldrich
|
| Telephone: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
|