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1900715-96-9

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1900715-96-9 Structure

1900715-96-9 Structure
IdentificationBack Directory
[Name]

Prucalopride Impurity 1
[CAS]

1900715-96-9
[Synonyms]

Prucalopride Impurity65
Prucalopride Succinate iMpuritP
7-Benzofurancarboxamide, 4-amino-5-chloro-N-[1-(3-methoxypropyl)-4-piperidinyl]-
4-?Amino-?5-?chloro-?N-?[1-?(3-?methoxypropyl)?-?4-?piperidinyl]?-7-?benzofurancarboxamid?e
[Molecular Formula]

C18H24ClN3O3
[MOL File]

1900715-96-9.mol
[Molecular Weight]

365.85
Chemical PropertiesBack Directory
[Boiling point ]

527.2±50.0 °C(Predicted)
[density ]

1.29±0.1 g/cm3(Predicted)
[pka]

13.13±0.20(Predicted)
Hazard InformationBack Directory
[Uses]

4-?Amino-?5-?chloro-?N-?[1-?(3-?methoxypropyl)?-?4-?piperidinyl]?-7-?benzofurancarboxamid?e is an impurity of Prucalopride Succinate (P838950(P)), which is a selective 5-HT4 receptor agonist used effective for chronic constipation, but is not currently approved in the U.S. Prucalopride is approved for the treatment of chronic constipation in Europe. In a more recent analytical study, 4-?Amino-?5-?chloro-?N-?[1-?(3-?methoxypropyl)?-?4-?piperidinyl]?-7-?benzofurancarboxamid?e was selectively separated and characterized as a process impurity of Prucalopride Succinate (P838950(P)) under stress conditions.
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