| Identification | Back Directory | [Name]
4(1H)-Quinazolinone, 2-(4-fluorophenyl)- | [CAS]
190838-76-7 | [Synonyms]
4-Hydroxy-2-(4-fluorophenyl)quinazoline
4(1H)-Quinazolinone, 2-(4-fluorophenyl)- | [Molecular Formula]
C14H9FN2O | [MDL Number]
MFCD00446433 | [MOL File]
190838-76-7.mol | [Molecular Weight]
240.23 |
| Chemical Properties | Back Directory | [Melting point ]
293-295 °C(Solv: ethanol (64-17-5)) | [Boiling point ]
393.1±44.0 °C(Predicted) | [density ]
1.31±0.1 g/cm3(Predicted) | [pka]
6.22±0.20(Predicted) |
| Hazard Information | Back Directory | [Description]
IUN38767, also known as FQ is a novel reversible mixed-type tyrosinase inhibitor. This product has no formal name at the moment. | [Uses]
FQ is a tyrosinase inhibitor that effectively inhibits the diphenolase activity of mushroom tyrosinase (IC50=120 μM). FQ can be used in the study of pigmentation[1]. | [References]
[1] Wang R, et al. 2-(4-Fluorophenyl)-quinazolin-4(3H)-one as a novel tyrosinase inhibitor: Synthesis, inhibitory activity, and mechanism. Bioorg Med Chem. 2016 Oct 1;24(19):4620-4625. DOI:10.1016/j.bmc.2016.07.068 |
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