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1911598-65-6

1911598-65-6 Structure

1911598-65-6 Structure
IdentificationBack Directory
[Name]

TAMRADBCO,5-isomer
[CAS]

1911598-65-6
[Synonyms]

TAMRADBCO,5-isomer
[Molecular Formula]

C46H42N4O5
[MOL File]

1911598-65-6.mol
[Molecular Weight]

730.85
Chemical PropertiesBack Directory
[solubility ]

soluble in DMSO, DMF
[pka]

3.436±0.36(predicted)
[Appearance]

dark colored solid
Hazard InformationBack Directory
[Description]

This product is a derivative of tetramethylrhodamine (TMR, TAMRA) containing a cyclooctyne moiety (dibenzocyclooctyne, DBCO). Pure 5-isomer.


DBCO reacts quickly and efficiently with azides by simply mixing the components without the need for a copper catalyst (so-called sterically promoted cycloaddition reaction (SPAAC)).


TAMRA DBCO can be used for the labeling of proteins, peptides, nucleic acids, and other molecules containing azide groups. TAMRA is often used as a FRET acceptor for FAM fluorophore. Can replace DyLight 549.

[Uses]

TAMRA DBCO, 5-isomer is a derivative of tetramethylrhodamine (TMR, TAMRA) containing a cyclooctyne moiety (dibenzocyclooctyne, DBCO). Pure 5-isomer. DBCO reacts quickly and efficiently with azides by simply mixing the components without the need for a copper catalyst (so-called sterically promoted cycloaddition reaction (SPAAC)). TAMRA DBCO can be used for the labeling of proteins, peptides, nucleic acids, and other molecules containing azide groups.
[Abs/Em Maxima]

541/567 nm
[Fluoresene quantum yield]

0.1
[Extinction Coefficient]

84000
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