| Identification | Back Directory | [Name]
2-HYDROXY-6-(TRIFLUOROMETHYL)NICOTINICACID
| [CAS]
191595-63-8 | [Synonyms]
2-Hydroxy-6-triflroromethylnicotinic acid
2-Hydroxy-6-(trifluromethyl)nicotinicacid
2-Hydroxy-6-(trifluoromethyl)nicotinic acid
3-carboxyl-6-trifluoromethyl-1H-pyridin-2-one
2-Hydroxy-6-triflroroMethyl-3-pyridinecarboxylic acid
2-oxo-6-(trifluoromethyl)-1H-pyridine-3-carboxylicaci
2-oxo-6-(trifluoromethyl)-1H-pyridine-3-carboxylic acid
2-HYDROXY-6-(TRIFLUOROMETHYL)NICOTINICACID ISO 9001：2015 REACH
3-Pyridinecarboxylic acid, 1,2-dihydro-2-oxo-6-(trifluoromethyl)-
2-Hydroxy-6-(trifluoromethyl)pyridine-3-carboxylic acid, 3-Carboxy-2-hydroxy-6-(trifluoromethyl)pyridine | [EINECS(EC#)]
671-164-4 | [Molecular Formula]
C7H4F3NO3 | [MDL Number]
MFCD01862657 | [MOL File]
191595-63-8.mol | [Molecular Weight]
207.11 |
| Chemical Properties | Back Directory | [Melting point ]
165-167°C | [Boiling point ]
328.9±42.0 °C(Predicted) | [density ]
1.632±0.06 g/cm3(Predicted) | [storage temp. ]
Inert atmosphere,Room Temperature | [form ]
solid | [pka]
1.99±0.20(Predicted) | [Appearance]
Light yellow to light brown Solid | [InChI]
1S/C7H4F3NO3/c8-7(9,10)4-2-1-3(6(13)14)5(12)11-4/h1-2H,(H,11,12)(H,13,14) | [InChIKey]
JPOIZUVDMRHIIT-UHFFFAOYSA-N | [SMILES]
OC(=O)c1ccc(nc1O)C(F)(F)F |
| Questions And Answer | Back Directory | [Uses]
2-Hydroxy-6-trifluoromethylnicotinic acid is an important pharmaceutical intermediate, mainly used in the fields of medicine, food, and feed. It can also be used as an intermediate for bactericides. |
| Hazard Information | Back Directory | [Synthesis]
Step 1, in a 250 ml three-necked flask, 10 g of 2-hydroxy-6-trifluoromethylnicotinonitrile, 16.2 g of phosphorus pentachloride and 40 g of phosphorus triclosan were added, heated to 100°C, followed by HPLC, and the reaction was carried out for 6 h. The |
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