ChemicalBook--->CAS DataBase List--->1917347-71-7

1917347-71-7

1917347-71-7 Structure

1917347-71-7 Structure
IdentificationBack Directory
[Name]

FCPR16
[CAS]

1917347-71-7
[Synonyms]

FCPR16
[Molecular Formula]

C18H16ClF2NO3
[MOL File]

1917347-71-7.mol
[Molecular Weight]

367.77
Chemical PropertiesBack Directory
[Boiling point ]

411.0±45.0 °C(predicted)
[density ]

1.368±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
[pka]

12.04±0.70(predicted)
Hazard InformationBack Directory
[Uses]

FCPR16 is a Phosphodiesterase 4 (PDE4) inhibitor. FCPR16 increases the levels of cAMP in SH-SY5Y cells. FCPR16 can be used in the study of Parkinson's disease[1].
[References]

[1] Zhong J, et al. Inhibition of phosphodiesterase 4 by FCPR16 protects SH-SY5Y cells against MPP+-induced decline of mitochondrial membrane potential and oxidative stress. Redox Biol. 2018 Jun;16:47-58. DOI:10.1016/j.redox.2018.02.008
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