| Identification | Back Directory | [Name]
1,4-DIHYDRO-2-METHYL-6-PHENYL-4-(PHENYLETHYNYL)-3,5-PYRIDINEDICARBOXYLIC ACID 3-ETHYL-5-[(3-NITROPHENYL)METHYL] ESTER | [CAS]
192053-05-7 | [Synonyms]
MRS 1334
1,4-Dihydro-2-methyl-6-phenyl-4-(phenylethynyl)-3,5-pyridinedicarboxylicacid3-ethyl-5-((3-nitrophenyl)methyl)ester
1,4-DIHYDRO-2-METHYL-6-PHENYL-4-(PHENYLETHYNYL)-3,5-PYRIDINEDICARBOXYLIC ACID 3-ETHYL-5-[(3-NITROPHENYL)METHYL] ESTER
3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2-methyl-6-phenyl-4-(2-phenylethynyl)-, 3-ethyl 5-[(4-nitrophenyl)methyl] ester | [Molecular Formula]
C31H26N2O6 | [MDL Number]
MFCD04113778 | [MOL File]
192053-05-7.mol | [Molecular Weight]
522.55 |
| Chemical Properties | Back Directory | [Boiling point ]
704.2±60.0 °C(Predicted) | [density ]
1.31±0.1 g/cm3(Predicted) | [storage temp. ]
Desiccate at -20°C | [solubility ]
Soluble to 100 mM in DMSO | [form ]
Powder | [pka]
1.46±0.70(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
MRS 1334 is a potent and highly selective hA3 antagonist. | [Definition]
ChEBI: 2-methyl-6-phenyl-4-(2-phenylethynyl)-1,4-dihydropyridine-3,5-dicarboxylic acid O3-ethyl ester O5-[(4-nitrophenyl)methyl] ester is a cinnamate ester. | [Biological Activity]
Potent and highly selective antagonist for the human adenosine A 3 receptor. K i values are 2.69 nM at hA 3 , and > 100 μ M at rat A 1 and rat A 2A receptors. | [IC 50]
hA3: 2.69 nM (Ki); rA1: >100 nM (Ki); rA2A: >100 nM (Ki) | [storage]
Desiccate at -20°C |
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https://www.chemicalbook.com/ShowSupplierProductsList13285/0.htm |
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R&D Systems, Inc
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