ChemicalBook--->CAS DataBase List--->192132-77-7

192132-77-7

192132-77-7 Structure

192132-77-7 Structure
IdentificationBack Directory
[Name]

2-(2-((tert-Butoxycarbonyl)amino)ethoxy)-ethyl 4-methylbenzenesulfonate
[CAS]

192132-77-7
[Synonyms]

NHBoc-PEG2-Tos
BocNH-PEG2-Tos
Tos-PEG2-NH-Boc
2-(2-((tert-Butoxycarbonyl)amino)ethoxy)-ethyl 4-methylbenzenesulfonate
[Molecular Formula]

C16H25NO6S
[MDL Number]

MFCD28506265
[MOL File]

192132-77-7.mol
[Molecular Weight]

359.44
Chemical PropertiesBack Directory
[Boiling point ]

504.6±40.0 °C(Predicted)
[density ]

1.179±0.06 g/cm3(Predicted)
[storage temp. ]

Storage temp. 2-8°C
[solubility ]

DMSO: 250 mg/mL (695.53 mM)
[form ]

Solid
[pka]

12.19±0.46(Predicted)
[color ]

White to off-white
Safety DataBack Directory
[Symbol(GHS) ]

Skull and Crossbones (GHS06)Health Hazard (GHS08)
GHS06,GHS08
[Signal word ]

Danger
[Hazard statements ]

H301-H311-H331-H341
[Precautionary statements ]

P201-P202-P261-P264-P270-P271-P280-P302+P352-P304+P340-P308+P313-P310-P330-P361-P403+P233-P405-P501
Hazard InformationBack Directory
[Uses]

Tos-PEG2-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
[Biological Activity]

Tos-PEG2-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
[IC 50]

PEGs; Alkyl/ether
[References]

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.
Spectrum DetailBack Directory
[Spectrum Detail]

2-(2-((tert-Butoxycarbonyl)amino)ethoxy)-ethyl 4-methylbenzenesulfonate(192132-77-7)1HNMR
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