| Identification | Back Directory | [Name]
2'-DEOXY-5-METHYLISOCYTIDINE | [CAS]
19316-88-2 | [Synonyms]
5-Methyl-2'-deoxyisouridine
2'-DEOXY-5-METHYLISOCYTIDINE
5-METHYL-2'-DEOXYISOCYTIDINE
2'-Decxy-5-methylisocytidine
2'-DEOXY-5-METHYLISOCYTIDINE
2-AMino-1-(2-deoxy-beta-D-ribofuranosyl)-5-Methyl-4(1H)-PyriMidinone
4(1H)-Pyrimidinone, 2-amino-1-(2-deoxy-β-D-erythro-pentofuranosyl)-5-methyl-
2-AMino-1-(2-deoxy-beta-D-erythro-pentofuranosyl)-5-Methyl-4(1H)-pyriMidinone
2-Amino-1-(2-deoxy-beta-D-ribofuranosyl)-5-methyl-4(1H)-Pyrimidinone,2'-Deoxy-5-methylisocytidine
2-amino-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidin-4(1H)-one | [Molecular Formula]
C10H15N3O4 | [MDL Number]
MFCD04973674 | [MOL File]
19316-88-2.mol | [Molecular Weight]
241.24 |
| Chemical Properties | Back Directory | [Boiling point ]
492.8±55.0 °C(Predicted) | [density ]
1?+-.0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
13.68±0.60(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
2′-Deoxy-5-methylisocytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
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