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1936429-80-9

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1936429-80-9 Structure

1936429-80-9 Structure
IdentificationBack Directory
[Name]

6-Bromo-7-(difluoromethyl)-1,2,3,4-tetrahydroquinoline
[CAS]

1936429-80-9
[Synonyms]

6-Bromo-7-(difluoromethyl)-1,2,3,4-tetrahydroquinoline
Quinoline, 6-bromo-7-(difluoromethyl)-1,2,3,4-tetrahydro-
[Molecular Formula]

C10H10BrF2N
[MDL Number]

MFCD32689499
[MOL File]

1936429-80-9.mol
[Molecular Weight]

262.09
Chemical PropertiesBack Directory
[Boiling point ]

328.6±42.0 °C(Predicted)
[density ]

1.485±0.06 g/cm3(Predicted)
[pka]

3.60±0.20(Predicted)
Hazard InformationBack Directory
[Uses]

6-Bromo-7-(difluoromethyl)-1,2,3,4-tetrahydroquinoline is an intermediate in the synthesis of GNE-781 (D447825), a derivative of a highly advanced, potent and selective bromodomain inhibitor of cyclic adenosine monophosphate response element binding protein (CBP). Inhibition of the bromodomain of the transcriptional regulator CBP/P300 is an especially interesting new therapeutic approach in oncology.
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