ChemicalBook--->CAS DataBase List--->1937270-46-6

1937270-46-6

1937270-46-6 Structure

1937270-46-6 Structure
IdentificationBack Directory
[Name]

PC Biotin-PEG3-Azide
[CAS]

1937270-46-6
[Synonyms]

PC Biotin-PEG3-Azide
[Molecular Formula]

C35H55N9O12S
[MDL Number]

MFCD28505552
[MOL File]

1937270-46-6.mol
[Molecular Weight]

825.94
Chemical PropertiesBack Directory
[storage temp. ]

-20°C
[solubility ]

DMSO : 50 mg/mL (60.54 mM; ultrasonic and warming and heat to 60°C)
[form ]

Oil
[color ]

Colorless to light yellow
[InChIKey]

PTNZFIYMARMNDM-MJUSKHNJSA-N
[SMILES]

S1[C@H]([C@H]3NC(=O)N[C@H]3C1)CCCCC(=O)NCCOCCOCCOCCNC(=O)CCCOc2c(cc(c(c2)[N+](=O)[O-])C(OC(=O)NCCCN=[N+]=[N-])C)OC
Safety DataBack Directory
[WGK Germany ]

WGK 3
[Storage Class]

5.2 - Organic peroxides and self-reacting hazardous materials
[Hazard Classifications]

Self-react. C
Hazard InformationBack Directory
[Description]

PC Biotin-PEG3-azide is useful for introducing a biotin moiety to alkyne-containing biomolecules using Click Chemistry. The hydrophilic PEG arm provides better solubility to the labeled molecules in aqueous media. Captured biomolecules can be efficiently photoreleased using near-UV, low intensity lamp (e.g. 365 nm lamp at 1-5 mW/cm2).
[Uses]

PC biotin-azide is an azide-activated photoclevable biotin probe that allows for reagent-free release of the captured biomolecules from streptavidin. This reagent contains a biotin moiety linked to an azide group through a spacer arm containing a photocleavable moiety. Captured biomolecules can be efficiently photoreleased, typically >90% in 5-25 minutes using an inexpensive, near-UV, low-intensity lamp (e.g. 365 nm lamp at 1-5 mW/cm2).
[IC 50]

Cleavable Linker
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