| Chemical Properties | Back Directory | [storage temp. ]
-20°C | [solubility ]
DMSO : 50 mg/mL (60.54 mM; ultrasonic and warming and heat to 60°C) | [form ]
Oil | [pka]
11.896±0.46(predicted) | [color ]
Colorless to light yellow | [InChIKey]
PTNZFIYMARMNDM-MJUSKHNJSA-N | [SMILES]
S1[C@H]([C@H]3NC(=O)N[C@H]3C1)CCCCC(=O)NCCOCCOCCOCCNC(=O)CCCOc2c(cc(c(c2)[N+](=O)[O-])C(OC(=O)NCCCN=[N+]=[N-])C)OC |
| Safety Data | Back Directory | [WGK Germany ]
WGK 3 | [Storage Class]
5.2 - Organic peroxides and self-reacting hazardous materials | [Hazard Classifications]
Self-react. C |
| Hazard Information | Back Directory | [Description]
PC Biotin-PEG3-azide is useful for introducing a biotin moiety to alkyne-containing biomolecules using Click Chemistry. The hydrophilic PEG arm provides better solubility to the labeled molecules in aqueous media. Captured biomolecules can be efficiently photoreleased using near-UV, low intensity lamp (e.g. 365 nm lamp at 1-5 mW/cm2). | [Uses]
PC biotin-azide is an azide-activated photoclevable biotin probe that allows for reagent-free release of the captured biomolecules from streptavidin. This reagent contains a biotin moiety linked to an azide group through a spacer arm containing a photocleavable moiety. Captured biomolecules can be efficiently photoreleased, typically >90% in 5-25 minutes using an inexpensive, near-UV, low-intensity lamp (e.g. 365 nm lamp at 1-5 mW/cm2). | [IC 50]
Cleavable Linker |
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