| Chemical Properties | Back Directory | [Sequence]
Ser-Pro-Thr-Cys-Ile-Pro-Ser-Gly-Gln-Pro-Cys-Pro-Tyr-Asn-Glu-Asn-Cys-Cys-Ser-Gln-Ser-Cys-Thr-Phe-Lys-Glu-Asn-Glu-Asn-Gly-Asn-Thr-Val-Lys-Arg-Cys-Asp (Disulfide bridge：Cys4-Cys18; Cys11-Cys22; Cys17-Cys36) |
| Hazard Information | Back Directory | [Uses]
ω-Hexatoxin-Hv1a is a neurotoxin that can be isolated from the venom spider (Hadronyche versuta).ω-Hexatoxin-Hv1a blocks voltage-gated calcium channels[1][2]. | [References]
[1] Powell ME, et al. Demonstrating the potential of a novel spider venom-based biopesticide for target-specific control of the small hive beetle, a serious pest of the European honeybee. J Pest Sci (2004). 2020;93(1):391-402. DOI:10.1007/s10340-019-01143-3
[2] Yang S, et al. Effect of insecticidal fusion proteins containing spider toxins targeting sodium and calcium ion channels on pyrethroid-resistant strains of peach-potato aphid (Myzus persicae). Pest Manag Sci. 2015 Jul;71(7):951-6. DOI:10.1002/ps.3872 |
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